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Biological Sciences : Diagnostics

Increased Plasma DNA Integrity in Cancer Patients (JHU Ref 4206)
This invention provides evidence that increased DNA integrity in plasma DNA can be detected in a substantial percentage of patients with potentially curable cancers at an apparently high specificity. This assay system, in contrast to other more sophisticated techniques, may offer a relatively simple and less expensive tool for cancer detection in the general population

Inventors
Ie-Ming Shih, Brant G. Wang 

Keywords
Diagnostic, detection, marker, point of use, Medical Device, diagnosis, Research Tool, PCR, Screening, detection, Cancer

Patents
Patent Pending

Reference
Wang BG, Huang H-Y, Chen Y-C, Bristow RE, Kassauei K, Cheng C-C, Roden R, Sokoll LJ, Chan DW, Shih I-M. Increased plasma DNA integrity in cancer patients. Cancer Res, July 15 issue, 2003.

Commercial Uses
The technology can be used to detect cancer using blood samples or other body fluids with high sensitivity and specificity.

Applicable Categories
  • Biological Sciences » Diagnostics


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    Jacqueline Walker
    The Johns Hopkins University
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    Baltimore, Maryland 21201
    Email: jwalke50@jhmi.edu
    Phone:410-516-8300
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